Name: Amide
SKU: 0

Basic Information

Item	Content
English Name	2-(3-Benzoylphenyl)-N-benzylpropanamide
CAS No.	166407-85-8
Molecular Formula	C23H21NO2
Molecular Weight	343.42
Functional Groups	Amide bond, aromatic ketone group, benzene ring

Physical and Chemical Properties

Appearance	White to off-white crystalline powder
Melting Point	118~122℃
Density	Approx. 1.18 g/cm³ (25℃)
Water Solubility	Practically insoluble in water
Solubility	Easily soluble in ethanol, ethyl acetate, dichloromethane, tetrahydrofuran and other organic solvents
Stability	Stable under normal temperature and pressure
Volatility	Low volatility

Main Chemical Properties

Reaction Type	Characteristics
Hydrolysis Reaction	Belongs to secondary amide, stable at room temperature; hydrolyzes under heating with strong acid or strong base to generate corresponding carboxylic acid and benzylamine
Reduction Reaction	Ketone carbonyl group can be reduced by sodium borohydride; amide bond is hard to be reduced by common reducing agents
Acid-base Property	Neutral overall, no obvious acidity or alkalinity
Polymerization	No polymerization activity
Oxidation Reaction	Aromatic ring is prone to oxidation reaction under strong oxidant condition
Substitution Reaction	Electrophilic substitution reaction can occur on benzene ring

Safety Information

Category	Details
Toxicity	Low toxicity, no acute high toxicity data
Contact Hazards	Mild irritation to skin, eyes and respiratory tract
Routes of Entry	Inhalation, skin contact, ingestion
Flammability & Explosion Hazard	Combustible; releases toxic fumes including nitrogen oxides and carbon monoxide when burned at high temperature
First-aid Measures	Skin contact: Rinse with plenty of clean water; Eye contact: Flush eyes thoroughly with water and seek medical advice; Inhalation: Move to fresh air immediately
Protective Measures	Wear dust-proof mask, rubber gloves and safety goggles; operate in well-ventilated place
Storage Conditions	Seal and store in cool dry place, keep away from heat source, strong acid, strong base and strong oxidants
Waste Disposal	Dispose as hazardous organic chemical waste, do not dump randomly
Incompatible Substances	Strong acids, strong alkalis and strong oxidizing substances

Product Usage

Amides are a class of organic compounds containing the -CONH2 group, widely used in pharmaceuticals, materials, chemicals, and agriculture. Their main applications include as active pharmaceutical ingredients, monomers for polymer materials, industrial solvents, and pesticides.